Cover Feature: Electrochemical Installation of CFH 2 −, CF 2 H−, CF 3 −, and Perfluoroalkyl Groups into Small Organic Molecules (Chem. Rec. 9/2021)
نویسندگان
چکیده
The cover picture displays fluoroalkyl radicals as reactive intermediates in the electrochemical (per)fluoroalkylation and representative examples of electrochemically fluoroalkylated small molecules. installation moieties into drug candidates significantly promotes their potency. Electrosynthesis is a sustainable powerful technology to tackle this challenging synthetic task. Consequently, fluoroalkylation organic molecules has become vivid area research, which surveyed by S. R. Waldvogel co-workers Record Review (DOI: 10.1002/tcr.202100065).
منابع مشابه
Packing conflicts in the Z' = 5 structure of CF(3)(CF(2))(3)(CH(2))(10)COOH.
Dimers of the partially fluorinated amphiphile 1-(perfluorobutyl)undecanoic acid, CF(3)(CF(2))(3)(CH(2))(10)COOH, crystallize in the same basic packing arrangement found for many n-alkyl carboxylic acids. The unit cell of the fluorinated compound, however, contains five independent molecules rather than the one found for most n-alkyl carboxylic acids including CH(3)(CH(2))(13)COOH. The structur...
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ژورنال
عنوان ژورنال: Chemical Record
سال: 2021
ISSN: ['1527-8999', '1528-0691']
DOI: https://doi.org/10.1002/tcr.202180905